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In order to study possible effects of microwave electromagnetic (EM) fields on neuronal activity, a real-time exposure system was designed and fabricated. The structure is suitable for electrophysiological recording in brain slices, a widely used in vitro methodology for investigations on neuronal function. The EM features of the structure were characterized both numerically and experimentally. Results indicate that the system is slightly radiating and that its field configuration produces minimum coupling with laboratory equipment. To determine the device efficiency, numerical and experimental dosimetry was conducted. The system exhibits high efficiency, with uniform distribution of the E- and H-fields and the specific absorption rate (SAR) in the biological sample.
Publication date: 
1 Nov 2007

Alessandra Paffi, Monica Pellegrino, Romeo Beccherelli, Francesca Apollonio, Micaela Liberti, Daniela Platano, Giorgio Aicardi, Guglielmo D'inzeo

Biblio References: 
Volume: 55 Issue: 11 Pages: 2463-2471
IEEE Transactions on Microwave Theory and Techniques