Figure 1. Plots displaying results from quantitative label free MS-based experiments. Normalized ion intensity values are reported as mean±SD of 3 technical replicates (independent LC-MS runs) x 5 biological replicates (different donors). Statistical significance is represented by letters above each error bar, with different letters indicating statistically significant differences (P< 0.05, unpaired t-test). Data analysis software (Compass DataAnalysis 4.0, Bruker Daltonics) was used for automated EIC peak height computing.